Research Paper Volume 12, Issue 20 pp 20163—20183

Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis

Figure 6. Effects of ciRS-7-related transfections (A) and miR-7-related transfections (B) on mRNA levels of autophagy-related genes Beclin1, LC3-II/I, and p62. Data represent the mean ± SD (n=3), * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. the IL-1β group.