Research Paper Volume 12, Issue 15 pp 15532—15545

circIQCH sponges miR-145 to promote breast cancer progression by upregulating DNMT3A expression

Figure 3. Downregulation of circIQCH inhibits the metastasis of breast cancer cells. (A, B) Wound-healing assays assess the impact of circIQCH on cell migration ability. (C, D) Transwell assays to evaluate cell migration capability. (E) HE-stained sections of lung metastases. (F) The number of metastases was counted and recorded.