Research Paper Volume 12, Issue 20 pp 20184—20197

Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice

Figure 2. Effects of IL-6 KO on cardiac dysfunction. (A) Survival rates of WT mice and IL-6 KO mice. (BF) LVPWT, LVEDD, LVESD, LVEF, and LVFS were determined at different time points by ultrasonic cardiography. (GI) The HRs of young mice and aging mice were measured. N=10-16 in each group. * p<0.05 vs. the young WT group; # p<0.05 vs. the aging WT group.