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Research Paper Volume 12, Issue 20 pp 20226—20234

Aerobic exercise induces tumor suppressor p16INK4a expression of endothelial progenitor cells in human skeletal muscle

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Figure 4. Aerobic exercise increases regenerative macrophage infiltration into human skeletal muscle. Arrows in the representative images indicate CD163+ cells (bright green) and nuclei (blue) surrounding myofibers in a muscle cross-section (A). This increase after 1-h cycling exercise (70% V̇O2max) was similar for both Placebo (PLA) and Rg1 trials (B). Scale bar = 50 μm. Data are expressed as mean and SEM. * Significant difference against Pre (Baseline), P < 0.01. Abbreviation: PLA, Placebo.