Research Paper Volume 12, Issue 20 pp 20226—20234

Aerobic exercise induces tumor suppressor p16INK4a expression of endothelial progenitor cells in human skeletal muscle

Figure 4. Aerobic exercise increases regenerative macrophage infiltration into human skeletal muscle. Arrows in the representative images indicate CD163+ cells (bright green) and nuclei (blue) surrounding myofibers in a muscle cross-section (A). This increase after 1-h cycling exercise (70% V̇O2max) was similar for both Placebo (PLA) and Rg1 trials (B). Scale bar = 50 μm. Data are expressed as mean and SEM. * Significant difference against Pre (Baseline), P < 0.01. Abbreviation: PLA, Placebo.