Research Paper Volume 12, Issue 20 pp 20235—20253

ARHGEF11 promotes proliferation and epithelial-mesenchymal transition of hepatocellular carcinoma through activation of β-catenin pathway

Figure 5. Knockdown of ARHGEF11 attenuates EMT, cell cycle progression and induces cell apoptosis via β-catenin-dependent way. (A) Correlation between the β-catenin and ARHGEF11 expression from TCGA HCC dataset analyzed by online CHIPbase. (B) β-Catenin expression from whole-cell lysates (up panel), the cytoplasmic and cell nuclear lysates (below panel) detected by western blot. (C) β-Catenin expression determined via immunofluorescence.