Research Paper Volume 12, Issue 15 pp 15682—15704

Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson’s disease patients with type 2 diabetes mellitus

Figure 3. ROC curves to evaluate the utility of novel risk factors (LDL-C and Fibrinogen, LDL-C, Fibrinogen) and traditional diagnostic factors (MDS-UPDRS, age, disease duration) for the discrimination of PD-DM patients with dementia from PD-DM patients without dementia. The AUC was 0.650 for fibrinogen (blue curve), 0.651 for LDL-C (black curve) and 0.717 for the combination of LDL-C and fibrinogen (green curve). The AUC was 0.564 for disease duration (red curve), 0.664 for age (purple curve) and 0.710 for MDS-UPDRS (orange curve). PD-DMD- patients with Parkinson’s Disease and type 2 diabetes mellitus and dementia; LDL-C- low density lipoprotein cholesterol; A- area under the curve; MDS-UPDRS- Movement Disorder Society–Unified Parkinson’s Disease Rating Scale; ROC- Receiver Operating Characteristic.