Research Paper Volume 12, Issue 20 pp 20254—20267

Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy

Figure 3. Unsupervised clustering of immune and stromal cells for 80 patients in the UM cohort. (A, B) The low infiltration and high infiltration cells in immune and stromal group; (C) Kaplan-Meier curves for overall survival (OS) of UM patients show that immune infiltration patterns are significantly associated with overall survival (log-rank test, P = 0.004); (D) Kaplan-Meier curves for OS of UM patients show that stromal infiltration patterns are significantly associated with overall survival (log-rank test, P = 0.03). Hazard ratios (HRs) and 95% CIs are for high or low immune and stromal infiltration risk.