Figure 1. Geographic areas of origin of the 36 skulls objects of the study. Red dots indicate the four sites where the six cases positive for MMTVenv-like sequences were identified: two in Ossi, Sardinia; two in Alghero, Sardinia; one in Luni, Liguria; one in Lucca, Tuscany. In four cases, the sequencing of both ENV1 and ENV 2 amplicons was accomplished; one of the ENV1 amplicons showed a C > T polymorphism, that did not cause an amino acid substitution: Ossi (ENV2), Luni (ENV1-C), Alghero (ENV1-C, ENV1-T). The two cases that dated back to the Copper Age came from Ossi, Sardinia.