Research Paper Volume 12, Issue 19 pp 19352—19364

CircPDZD8 promotes gastric cancer progression by regulating CHD9 via sponging miR-197-5p

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Effect of circPDZD8 on tumor growth of gastric cancer in vivo. (A) Tumor volume was measured at indicated time points after injection of SGC-7901 cells transfected with lv-sh-circPDZD8 or lv-sh-control. (B) Tumor weight was measured after the mice were sacrificed. (C, D) The expression levels of circPDZD8 and miR-197-5p in tumor tissues were measured by RT-qPCR. (E, F) The mRNA and protein expression levels of CHD9 in tumor tissues were detected by RT-qPCR and western blot, respectively; *** P < 0.001.