Research Paper Advance Articles pp 23647—23667

Identification of the novel Np17 oncogene in human leukemia

Figure 1. Analyses of Np17 amino acid sequence and potential motifs. (A) Amino acid sequence of Np17 protein. Putative motifs corresponding to nuclear localization signal (NLS), N-glycosylation site, PKC phospho site and Grb2 motif (P-x-x-P-x-R) are shown in red, blue, green and purple, respectively. (B) Alignment of Np17 aa sequence between 59 and 117 aa with viral Np9. (C) Schematic representations of putative NLS motif and Np9 homeodomain of Np17 protein.