Volume 12, Issue 23

15 December, 2020
pp 23422—24475

About the Cover

The cover features Figure 10 "Proposed mechanism of the regulation of galectin-9 expression in human cancer and embryonic stage at low and normal oxygen availability stages“ from Selnø et al.

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Table of Contents

Editorials

Regulation of glucose homeostasis by calorie restriction and periodic fasting

Volha Mezhnina, Roman Kondratov,

https://doi.org/10.18632/aging.104217 pp 23422—23424

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Bacteria boost host NAD metabolism

Igor Shats, Xiaoling Li,

https://doi.org/10.18632/aging.104219 pp 23425—23426

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Research Papers

COVID-19
Evolution of COVID-19 in patients with autoimmune rheumatic diseases

Rongrong Pang, Jun Zhao, Zhenhua Gan, Zhiliang Hu, Xiang Xue, Yanjun Wu, Qinghua Qiao, Aifang Zhong, Xinyi Xia, Hui Liao, Zhihua Wang, Libo Zhang,

https://doi.org/10.18632/aging.202193 pp 23427—23435

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COVID-19
Clinical characteristics and fatal outcomes of hypertension in patients with severe COVID-19

Xiaocheng Cheng, Guoqiang Cai, Xuesong Wen, Lei Gao, Dan Jiang, Min Sun, Shu Qin, Jianzhong Zhou, Dongying Zhang,

https://doi.org/10.18632/aging.104019 pp 23436—23449

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COVID-19
Incidence of cerebrovascular disease as a comorbidity in patients with COVID-19: a meta-analysis

Jun Zhang, Haili Wang, Min Wei, Hengzhu Zhang, Boming Xia, Xingdong Wang, Yunlong Pei, Lun Dong, Yuping Li,

https://doi.org/10.18632/aging.104086 pp 23450—23463

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COVID-19
Risk factors for COVID-19 patients with cardiac injury: pulmonary ventilation dysfunction and oxygen inhalation insufficiency are not the direct causes

Sucheng Mu, Wei Wei, Chaoyuan Jin, Ning Pu, Kaihuan Yu, Guorong Gu, Zhe Luo, Chaoyang Tong, Yi Han,

https://doi.org/10.18632/aging.104148 pp 23464—23477

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Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells

Anette Teo Hansen Selnø, Stephanie Schlichtner, Inna M. Yasinska, Svetlana S. Sakhnevych, Walter Fiedler, Jasmin Wellbrock, Elena Klenova, Ludmila Pavlova, Bernhard F. Gibbs, Martin Degen, Isabelle Schnyder, Nijas Aliu, Steffen M. Berger, Elizaveta Fasler-Kan, Vadim V. Sumbayev,

https://doi.org/10.18632/aging.202343 pp 23478—23496

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Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice

Clara Sciorati, Riccardo Gamberale, Antonella Monno, Lorena Citterio, Chiara Lanzani, Rebecca De Lorenzo, Giuseppe A. Ramirez, Antonio Esposito, Paolo Manunta, Angelo A. Manfredi, Patrizia Rovere-Querini,

https://doi.org/10.18632/aging.202200 pp 23497—23508

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FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease

Randi Chen, Brian J. Morris, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Philip M.C. Davy, Richard C. Allsopp, Bradley J. Willcox,

https://doi.org/10.18632/aging.202175 pp 23509—23524

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Mutation in histone deacetylase HDA-3 leads to shortened locomotor healthspan in Caenorhabditis elegans

Kazuto Kawamura, Ichiro N. Maruyama,

https://doi.org/10.18632/aging.202296 pp 23525—23547

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PsychoAge and SubjAge: development of deep markers of psychological and subjective age using artificial intelligence

Alex Zhavoronkov, Kirill Kochetov, Peter Diamandis, Maria Mitina,

https://doi.org/10.18632/aging.202344 pp 23548—23577

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Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, Marion Fernandez-Berrocal, Rouan Yao, Valentyn Oksenych,

https://doi.org/10.18632/aging.202346 pp 23578—23597

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Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway

Liansheng Sha, Deying Ma, Cuili Chen,

https://doi.org/10.18632/aging.103546 pp 23598—23608

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Inhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α

Lianping Gou, Cheng Xue, Xiaoyan Tang, Zhiyuan Fang,

https://doi.org/10.18632/aging.103563 pp 23609—23618

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Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

Ya-Jen Chiu, Shu-An Lin, Wan-Ling Chen, Te-Hsien Lin, Chih-Hsin Lin, Ching-Fa Yao, Wenwei Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen, Chiung-Mei Chen,

https://doi.org/10.18632/aging.103700 pp 23619—23646

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Identification of the novel Np17 oncogene in human leukemia

Bowen Wu, Yichao Gan, Ying Xu, Zhaoxing Wu, Ganyu Xu, Ping Wang, Chen Wang, Zhipeng Meng, Mengyuan Li, Jiawei Zhang, Haifeng Zhuang, Xuzhao Zhang, Linlin Yang, Jinfan Li, Xiaoxian Gan, Xiaofang Yu, Wendong Huang, Ying Gu, Rongzhen Xu,

https://doi.org/10.18632/aging.103808 pp 23647—23667

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DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder cancer

Kai Xu, Binshen Chen, Bingkun Li, Chaoming Li, Yiming Zhang, Ning Jiang, Bin Lang,

https://doi.org/10.18632/aging.103820 pp 23668—23683

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Hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated endoplasmic reticulum stress

Bing Zhuan, Xi Wang, Ming-Deng Wang, Zhi-Cai Li, Qun Yuan, Jun Xie, Zhao Yang,

https://doi.org/10.18632/aging.103892 pp 23684—23697

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The ZiBuPiYin recipe regulates proteomic alterations in brain mitochondria-associated ER membranes caused by chronic psychological stress exposure: Implications for cognitive decline in Zucker diabetic fatty rats

Huiying Xu, Wen Zhou, Libin Zhan, Hua Sui, Lijing Zhang, Chunyan Zhao, Xiaoguang Lu,

https://doi.org/10.18632/aging.103894 pp 23698—23726

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Neurofilament light chain predicts risk of recurrence in cerebral amyloid angiopathy-related intracerebral hemorrhage

Xin Cheng, Ya Su, Qiong Wang, Feng Gao, Xiaofei Ye, Yiqing Wang, Yiwei Xia, Jiayu Fu, Yong Shen, Rustam Al-Shahi Salman, Qiang Dong,

https://doi.org/10.18632/aging.103927 pp 23727—23738

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Red light exaggerated sepsis-induced learning impairments and anxiety-like behaviors

Bing Xie, Yujing Zhang, Hong Qi, Hua Yao, You Shang, Shiying Yuan, Jiancheng Zhang,

https://doi.org/10.18632/aging.103940 pp 23739—23760

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Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma

Xiangyu Zhai, Wei Wang, Yunlong Ma, Yijia Zeng, Dandan Dou, Haoning Fan, Jianping Song, Xin Yu, Danqing Xin, Gang Du, Zhengchen Jiang, Hao Zhang, Xinlu Zhang, Bin Jin,

https://doi.org/10.18632/aging.103964 pp 23761—23777

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Colon cancer combined with obesity indicates improved survival- research on relevant mechanism

Zhou Yang, Xiyi Wei, Yitong Pan, Zhijun Min, Jingyuan Xu, Bo Yu,

https://doi.org/10.18632/aging.103972 pp 23778—23794

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Demethoxycurcumin analogue DMC-BH exhibits potent anticancer effects on orthotopic glioblastomas

Lei Shi, Guan Sun, Yong Zhang,

https://doi.org/10.18632/aging.103981 pp 23795—23807

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Effect of Klotho protein during porcine oocyte maturation via Wnt signaling

Eui Hyun Kim, Anukul Taweechaipaisankul, Muhammad Rosyid Ridlo, Geon A Kim, Byeong Chun Lee,

https://doi.org/10.18632/aging.104002 pp 23808—23821

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Calreticulin increases growth and progression of natural killer/T-cell lymphoma

Yan Zheng, Chuntuan Li, Pengliang Xin, Qunyi Peng, Weiyu Zhang, Shengquan Liu, Xiongpeng Zhu,

https://doi.org/10.18632/aging.104030 pp 23822—23835

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Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression

Pei Xu, Lei Wang, Xiao Xie, Fengqing Hu, Qi Yang, Rui Hu, Lianyong Jiang, Fangbao Ding, Ju Mei, Jianhui Liu, Haibo Xiao,

https://doi.org/10.18632/aging.104037 pp 23836—23848

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Integrative analysis reveals novel driver genes and molecular subclasses of hepatocellular carcinoma

Liguang Yang, Zhengtao Zhang, Yidi Sun, Shichao Pang, Qianlan Yao, Ping Lin, Jinming Cheng, Jia Li, Guohui Ding, Lijian Hui, Yixue Li, Hong Li,

https://doi.org/10.18632/aging.104047 pp 23849—23871

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Apigenin-7-O-β-D-(-6”-p-coumaroyl)-glucopyranoside treatment elicits a neuroprotective effect through GSK-3β phosphorylation-mediated Nrf2 activation

Jingwen Wang, Shiquan Wang, Sisi Sun, Yunyang Lu, Kai Gao, Chao Guo, Ruili Li, Weiwei Li, Xian Zhao, Haifeng Tang, Aidong Wen, Min Cai, Wei Zhang,

https://doi.org/10.18632/aging.104050 pp 23872—23888

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Cohort profile: the Diet and Healthy Aging (DaHA) study in Singapore

Rongjun Yu, Ye Sun, Kaisy Xinhong Ye, Qiushi Feng, Su Lin Lim, Rathi Mahendran, Irwin Kee-Mun Cheah, Roger Sik Yin Foo, Ru Yuan Chua, Xinyi Gwee, Marie Loh, Rani Sarmugam, Wei Wei Thwe Khine, Yin Xia Chao, Anis Larbi, Yuan Kun Lee, Alan Prem Kumar, Brian K. Kennedy, Ee Heok Kua, Lei Feng,

https://doi.org/10.18632/aging.104051 pp 23889—23899

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Female-specific effects of the catechol-O-methyl transferase Val¹⁵⁸Met gene polymorphism on working memory-related brain function

Jialing Fan, Caishui Yang, Zhen Liu, He Li, Yan Han, Kewei Chen, Chuansheng Chen, Jun Wang, Zhanjun Zhang,

https://doi.org/10.18632/aging.104059 pp 23900—23916

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Molecular subtypes based on DNA promoter methylation predict prognosis in lung adenocarcinoma patients

Shanping Shi, Mingjun Xu, Yang Xi,

https://doi.org/10.18632/aging.104062 pp 23917—23930

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Clinical and prognostic pan-cancer analysis of m6A RNA methylation regulators in four types of endocrine system tumors

Kai Li, Haiqing Luo, Hui Luo, Xiao Zhu,

https://doi.org/10.18632/aging.104064 pp 23931—23944

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In-depth transcriptomic analyses of LncRNA and mRNA expression in the hippocampus of APP/PS1 mice by Danggui-Shaoyao-San

Zhenyan Song, Fuzhou Li, Chunxiang He, Jingping Yu, Ping Li, Ze Li, Miao Yang, Shaowu Cheng,

https://doi.org/10.18632/aging.104068 pp 23945—23959

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The long noncoding RNA HCG18 participates in PM2.5-mediated vascular endothelial barrier dysfunction

Shiwen Wang, Yuyin Lin, Yue Zhong, Maozhou Zhao, Wei Yao, Xiaohui Ren, Qin Wang, Xiaolan Guo, Qian-Qian Zhang, Jianwei Dai,

https://doi.org/10.18632/aging.104073 pp 23960—23973

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Effect of lncRNA WT1-AS regulating WT1 on oxidative stress injury and apoptosis of neurons in Alzheimer's disease via inhibition of the miR-375/SIX4 axis

Quanbao Wang, Xiumin Ge, Jie Zhang, Licheng Chen,

https://doi.org/10.18632/aging.104079 pp 23974—23995

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Hsa_circ_0048179 attenuates free fatty acid-induced steatosis via hsa_circ_0048179/miR-188-3p/GPX4 signaling

Wenjun Yang, Jinduo Zhao, Ye Zhao, Wenfeng Li, Liang Zhao, Yi Ren, Rongying Ou, Yunsheng Xu,

https://doi.org/10.18632/aging.104081 pp 23996—24008

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Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer

Wencheng Kong, Xinchun Liu, Guang Yin, Sixin Zheng, Akao Zhu, Panpan Yu, Yuqiang Shan, Rongchao Ying, Jian Zhang,

https://doi.org/10.18632/aging.104082 pp 24009—24022

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Islet transplantation modulates macrophage to induce immune tolerance and angiogenesis of islet tissue in type I diabetes mice model

Yang Li, Xiaoming Ding, Xiaohui Tian, Jin Zheng, Chenguang Ding, Xiao Li, Xiaojun Hu, Yuxi Qiao, Ying Wang, Wujun Xue,

https://doi.org/10.18632/aging.104085 pp 24023—24032

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lncRNA DLEU2 acts as a miR-181a sponge to regulate SEPP1 and inhibit skeletal muscle differentiation and regeneration

Yao Wang, Zhi-Jie Zhao, Xue-Ran Kang, Tao Bian, Zhe-Min Shen, Yang Jiang, Bao Sun, Han-Bing Hu, Yi-Sheng Chen,

https://doi.org/10.18632/aging.104095 pp 24033—24056

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Age-related DNA methylation changes are sex-specific: a comprehensive assessment

Igor Yusipov, Maria Giulia Bacalini, Alena Kalyakulina, Mikhail Krivonosov, Chiara Pirazzini, Noémie Gensous, Francesco Ravaioli, Maddalena Milazzo, Cristina Giuliani, Maria Vedunova, Giovanni Fiorito, Amedeo Gagliardi, Silvia Polidoro, Paolo Garagnani, Mikhail Ivanchenko, Claudio Franceschi,

https://doi.org/10.18632/aging.202251 pp 24057—24080

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Minimizing sedentary behavior (without increasing medium-to-vigorous exercise) associated functional improvement in older women is somewhat dependent on a measurable increase in muscle size

Dale Grant, David Tomlinson, Kostas Tsintzas, Petra Kolić, Gladys Onambélé-Pearson,

https://doi.org/10.18632/aging.202265 pp 24081—24100

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Predicting the outcome of non-pharmacological treatment for patients with dementia-related mild cognitive impairment

Yoshihito Shigihara, Hideyuki Hoshi, Jesús Poza, Víctor Rodríguez-González, Carlos Gómez, Takao Kanzawa,

https://doi.org/10.18632/aging.202270 pp 24101—24116

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Dilated cardiomyopathy impairs mitochondrial biogenesis and promotes inflammation in an age- and sex-dependent manner

Maria Luisa Barcena, Sofya Pozdniakova, Natalie Haritonow, Pavelas Breiter, Anja A. Kühl, Hendrik Milting, Istvan Baczko, Yury Ladilov, Vera Regitz-Zagrosek,

https://doi.org/10.18632/aging.202283 pp 24117—24133

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Detection of NUCB2/nesfatin-1 in cerebrospinal fluid of multiple sclerosis patients

Masaru Shimizu, Taizo Manome, Masumi Kumami, Kouzou Matsumura, Kazuaki Kanai, Kenju Shimomura, Yuko Maejima,

https://doi.org/10.18632/aging.202287 pp 24134—24140

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Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution

Cavin K. Ward-Caviness, Armistead G. Russell, Anne M. Weaver, Erik Slawsky, Radhika Dhingra, Lydia Coulter Kwee, Rong Jiang, Lucas M. Neas, David Diaz-Sanchez, Robert B. Devlin, Wayne E. Cascio, Kenneth Olden, Elizabeth R. Hauser, Svati H. Shah, William E. Kraus,

https://doi.org/10.18632/aging.202341 pp 24141—24155

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Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice

Fan Yu, Riyue Jiang, Wei Han, Gaofeng Zhan, Xiaolin Xu, Xiaohong Jiang, Long Wang, Shoukui Xiang, Qin Zhou, Cunming Liu, Bin Zhu, Fei Hua, Chun Yang,

https://doi.org/10.18632/aging.104101 pp 24156—24167

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Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways

Hao-Chun Chuang, Kun-Ling Tsai, Kuen-Jer Tsai, Ting-Yuan Tu, Yan-Jye Shyong, I-Ming Jou, Che-Chia Hsu, Shu-Shien Shih, Yuan-Fu Liu, Cheng-Li Lin,

https://doi.org/10.18632/aging.104105 pp 24168—24183

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Construction of circRNA-based ceRNA network to reveal the role of circRNAs in the progression and prognosis of metastatic clear cell renal cell carcinoma

Xiyi Wei, Yuxiang Dong, Xinglin Chen, Xiaohan Ren, Guangyao Li, Yamin Wang, Yichun Wang, Tongtong Zhang, Shangqian Wang, Chao Qin, Ninghong Song,

https://doi.org/10.18632/aging.104107 pp 24184—24207

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SRT2183 impairs ovarian cancer by facilitating autophagy

Tingting Sun, Yanfen Hu, Weipeng He, Yuru Shang, Xiaohong Yang, Liyun Gong, Xianbin Zhang, Peng Gong, Guofen Yang,

https://doi.org/10.18632/aging.104126 pp 24208—24218

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Stroke risk in hypertrophic cardiomyopathy patients with atrial fibrillation: a nationwide database study

Jung-Chi Hsu, Ya-Ting Huang, Lian-Yu Lin,

https://doi.org/10.18632/aging.104133 pp 24219—24227

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The value of a metabolic reprogramming-related gene signature for pancreatic adenocarcinoma prognosis prediction

Zhen Tan, Yubin Lei, Jin Xu, Si Shi, Jie Hua, Bo Zhang, Qingcai Meng, Jiang Liu, Yiyin Zhang, Miaoyan Wei, Xianjun Yu, Chen Liang,

https://doi.org/10.18632/aging.104134 pp 24228—24241

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TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy

Jie Chen, Yufei Ma, Zhijie Yang, Haiyang Lan, Guangliang Liu, Ye Zhang, Huiqiang Xia, Xiaofang Wang, Fei Han, Xiaolin Tu, Bo Liu,

https://doi.org/10.18632/aging.104160 pp 24242—24254

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Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines

Zhi Zhang, Cheng-Zu He, Ya-Qin Qin, Jian-Jun Liao, Shang-Tao Huang, Steven Mo, Hong-Mian Li, Jian-Yan Lin,

https://doi.org/10.18632/aging.104195 pp 24255—24269

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Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway

Jing Zhang, Lelin Huang, Xing Shi, Liu Yang, Fuzhou Hua, Jianyong Ma, Wengen Zhu, Xiao Liu, Rui Xuan, Yunfeng Shen, Jianping Liu, Xiaoyang Lai, Peng Yu,

https://doi.org/10.18632/aging.202143 pp 24270—24287

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Sensory impairment and all-cause mortality among the elderly adults in China: a population-based cohort study

Ji Sun, Lin Li, Jiangwei Sun,

https://doi.org/10.18632/aging.202198 pp 24288—24300

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Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling

Tiao Li, Kristen V. Fanning, Toru Nyunoya, Yan Chen, Chunbin Zou,

https://doi.org/10.18632/aging.202210 pp 24301—24317

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Isoquercitrin induces apoptosis and autophagy in hepatocellular carcinoma cells via AMPK/mTOR/p70S6K signaling pathway

Liyan Shui, Weina Wang, Mingjie Xie, Bingjue Ye, Xian Li, Yanning Liu, Min Zheng,

https://doi.org/10.18632/aging.202237 pp 24318—24332

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Intra-tumoral heterogeneity and immune responses predicts prognosis of gastric cancer

Wanjing Feng, Yue Wang, Siyuan Chen, Xiaodong Zhu,

https://doi.org/10.18632/aging.202238 pp 24333—24344

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Implication of integrins α3β1 and α5β1 in invasion and anoikis of SK-Mel-147 human melanoma cells: non-canonical functions of protein kinase Akt

Nadezhda I. Kozlova, Galina E. Morozevich, Nina M. Gevorkian, Albert E. Berman,

https://doi.org/10.18632/aging.202243 pp 24345—24356

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A forced swim-based rat model of premenstrual depression: effects of hormonal changes and drug intervention

Sheng Wei, Xiwen Geng, Zifa Li, Kaiyong Xu, Minghui Hu, Hongyun Wu, Wei Shi, Mingqi Qiao,

https://doi.org/10.18632/aging.202249 pp 24357—24370

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Mental awareness improved mild cognitive impairment and modulated gut microbiome

Wei Wei Thwe Khine, Miao Lian Voong, Ted Kheng Siang Ng, Lei Feng, Grishma Avinash Rane, Alan Prem Kumar, Ee Heok Kua, Ratha Mahendran, Rathi Mahendran, Yuan-Kun Lee,

https://doi.org/10.18632/aging.202277 pp 24371—24393

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E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc

Lijia Zhong, Yuanyuan Zhang, Mengyao Li, Yinjing Song, Danhui Liu, Xin Yang, Dehua Yang, Hao Qu, Lihua Lai, Qingqing Wang, Zhimin Chen,

https://doi.org/10.18632/aging.202293 pp 24394—24423

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FOXM1/DVL2/Snail axis drives metastasis and chemoresistance of colorectal cancer

Yuhan Yang, Hequn Jiang, Wanxin Li, Linyi Chen, Wanglong Zhu, Yu Xian, Zhengyu Han, Lan Yin, Yao Liu, Yi Wang, Kejian Pan, Kun Zhang,

https://doi.org/10.18632/aging.202300 pp 24424—24440

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Reviews

Caloric restriction: implications for sarcopenia and potential mechanisms

Wen-Qing Xie, Wen-Feng Xiao, Kun Tang, Yu-Xiang Wu, Pei-Wu Hu, Yu-Sheng Li, Yu Duan, Shan Lv,

https://doi.org/10.18632/aging.103987 pp 24441—24452

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COVID-19
Role of angiotensin-converting enzyme 2 in neurodegenerative diseases during the COVID-19 pandemic

Zhenyu Li, Xiaolin Xu, Meiling Yang, Jianping Feng, Cunming Liu, Chun Yang,

https://doi.org/10.18632/aging.103993 pp 24453—24461

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COVID-19
Clinical challenges in cancer patients with COVID-19: Aging, immunosuppression, and comorbidities

Lu Wang, Yinan Sun, Ye Yuan, Qi Mei, Xianglin Yuan,

https://doi.org/10.18632/aging.104205 pp 24462—24474

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Correction

Correction for: TAp63γ influences mouse cartilage development

Qian Wang, Na Li, Fangzhou Chen, Ruoxuan Hei, Junxia Gu, Yaojuan Lu, Lichun Sun, Qiping Zheng,

https://doi.org/10.18632/aging.104221 pp 24475

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