Research Paper Advance Articles pp 24288—24300
Sensory impairment and all-cause mortality among the elderly adults in China: a population-based cohort study
- 1 Department of Pathology, Eye and ENT Hospital, Fudan University, Shanghai, China
- 2 School of Medical Sciences, Örebro University, Örebro, Sweden
- 3 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
- 4 Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Received: August 3, 2020 Accepted: October 27, 2020 Published: November 26, 2020https://doi.org/10.18632/aging.202198
How to Cite
Copyright: © 2020 Sun et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
With age-related functional deterioration, sensory impairment including vision impairment (VI), hearing impairment (HI), and dual sensory impairment (DSI) usually occurred among the elderly population, causing a decrease in functional capacity and quality of life. The study aimed to explore how sensory impairment is associated with the risk of all-cause mortality among the elderly adults in China. We prospectively investigated the association among 37,076 participants enrolled from 1998 to 2019 in the Chinese Longitudinal Healthy Longevity Survey. We also, as a sensitivity analysis, explored the association among 11,365 newly incident sensory impairment participants. Cox regression model with sensory impairment as a time-varying exposure was performed to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs). Compared with participants without sensory impairment, those with VI (HR=1.20, 95% CI: 1.15-1.24), HI (HR=1.26, 95% CI: 1.21-1.31), and DSI (HR: 1.46, 95% CI=1.41-1.52) had significant higher risk of all-cause mortality after adjusting for potential confounders. These associations were robust among subgroup analyses stratified by sex and entry age, and sensitivity analyses performed among newly incident sensory impairment participants. In conclusion, sensory impairment was associated with higher mortality risk among the elderly adults in China.