Research Paper Volume 12, Issue 15 pp 15756—15770

MiR-483 induces senescence of human adipose-derived mesenchymal stem cells through IGF1 inhibition

Figure 2. MiR-483 expression during the adipogenic differentiation of hADSCs. (A, B) Small-RNA sequencing was performed to profile miRNAs with variant expression during adipogenic differentiation of hADSCs. Data are expressed as the number of reads and (C) differentially expressed miRNA genes. (D, E) The relative expression of miR-483-5p and miR-483-3p was validated by RT-qPCR. (F) The location and classification of miR-483.