Research Paper Volume 12, Issue 19 pp 19375—19398
HOXC10 promotes tumour metastasis by regulating the EMT-related gene Slug in ovarian cancer
Figure 1. Overexpression of HOXC10 is associated with poor prognosis in OC patients. (A) Kaplan-Meier survival curves for OC patients (PFS; n = 1207). HR=1.17, P=0.031. (B) HOXC10 protein expression in normal ovarian tissues (case 1) and OC patient tissues (case 2, low expression of HOXC10; case 3, high expression of HOXC10) was assessed by IHC staining. Scale bars, 50 μm. (C) IHC positive rate scores for HOXC10 in normal tissues and each group of OC patient tissues. P<0.0001. (D) Kaplan-Meier survival curves for 158 OC patients. HR=1.754, P=0.0096.