Research Paper Volume 12, Issue 19 pp 19375—19398

HOXC10 promotes tumour metastasis by regulating the EMT-related gene Slug in ovarian cancer

Figure 3. HOXC10 promotes OC cell migration by regulating Slug transcription. (M, N) Rescue experiment using 8910 cells cotransfected with the HOXC10 overexpression plasmid, siRNA targeting Slug, empty vector or negative control. P<0.0001, P<0.0001, and P=0.0832; P<0.0001, P=0.0107, and P=0.5562. Scale bars, 200 μm and 100 μm, respectively. (O, P) Rescue experiment using 8910 cells cotransfected with siRNA targeting HOXC10, the Slug overexpression plasmid, negative control or empty vector. P<0.0001, P<0.0001, and P=0.1647; P<0.0001, P=0.0107, and P=0.5562. Scale bars, 200 μm and 100 μm, respectively.