Research Paper Volume 12, Issue 20 pp 20366—20379

miR-140-3p inhibits bladder cancer cell proliferation and invasion by targeting FOXQ1

Figure 5. miR-140-3p suppresses the growth of BCa cells in vivo. (A) Macroscopic appearance of murine tumor xenografts. (B) Weights of tumors in 2 groups were measured using electronic scales. (C) Summary of tumor volume, which were measured weekly. (D) Representative immunohistochemical staining of Ki-67 and FOXQ1 in murine BCa cell xenografts. (E) The expression of miR-140-3p in xenografts was detected using qRT-PCR. (F) The expression of FOXQ1 in xenografts was detected using qRT-PCR. (BF) Each sample was run in triplicate and used in multiple experiments to determine the mean ± SD. *P < 0.05; **P < 0.01 compared to controls.