Research Paper Volume 12, Issue 22 pp 22564—22581

Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL

Figure 5. GFRAL and GDF-15 colocalize in human pancreatic cancer cells. (AD) H.E images for 4 patient samples with histologically confirmed PDAC; (EH) Immunofluorescence staining for GFRAL and nuclei counterstained with DAPI; (IL) Immunofluorescence staining for GDF-15 and nuclei counterstained with DAPI; (MP) Merged images of GFRAL, GDF-15, and DAPI staining.