Research Paper Volume 12, Issue 22 pp 22582—22598

linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3

Figure 1. The expression and clinical significance of linc00968 in NSCLC. (A) Volcano plot showing the differential genes (red dots and blue dots) in the expression microarray. (B) Heatmap of GSE19804 and GSE18842. (C) Venn diagram showing the common downregulated or upregulated lncRNAs in two GEO dataset. (D) linc00968 expression in LUAD and LUSC from TCGA, with red boxplot referring to cancer sample and gray boxplot referring to normal sample. (E) Survival analysis of linc00968 in LUAD and LUSC from Kaplan-Meier survival plot. (F) Survival analysis of linc00968 in LUAD from TCGA. (G) Expression of linc00968 in LUAD tissues and para-carcinoma tissues examined by qRT-PCR assay. **P<0.01 versus the para-carcinoma tissues. (HI) The expression levels of linc00968 in LUAD patients with different pathological stages and lymph node metastasis. **P<0.01 versus the I-II or patients with no lymph node metastasis.