Research Paper Volume 12, Issue 21 pp 21236—21252

IGF2 loss of imprinting enhances colorectal cancer stem cells pluripotency by promoting tumor autophagy

Figure 4. The regulation of miRNAs on IR-A expression. (A) the IR-A and IGF1R protein and mRNA expression in CRC and normal cells; (B) the expression levels of miRNA-195 and miRNA-15b in CRC patients; (C) the IR-A expression of IGF2 LOI CRC cells transfected with miRNA-195 mimics.