Research Paper Volume 12, Issue 21 pp 21344—21354

Soy isoflavones ameliorate the cognitive dysfunction of Goto-Kakizaki rats by activating the Nrf2-HO-1 signalling pathway

Figure 5. Effects of SIF on oxidative stress genes. Relative mRNA expression of Nrf2(A), HO-1(B) and NQO1(C) in the hippocampus. The results are shown as the mean ±standard deviation (n=5 per group). *p < 0.05 or **p < 0.01 vs. the CON group, #p <0.05 or ##p <0.01 vs. the DM group.