Research Paper Volume 12, Issue 21 pp 21376—21390

The mechanism of submandibular gland dysfunction after menopause may be associated with the ferroptosis

Figure 3. Mitochondria dysfunction. (A) Electron microscopy of submandibular gland in the CON and OVX groups. (B) Western blotting of antioxidant enzyme; SOD and catalase and control VDAC in the CON and OVX groups. (C) ROS generation in the CON and OVX groups. CON = control, OVX = ovariectomy, SOD = superoxide dismutase, CAT = catalase, VDAC = voltage-dependent anion channel.