Research Paper Advance Articles pp 23698—23726

The ZiBuPiYin recipe regulates proteomic alterations in brain mitochondria-associated ER membranes caused by chronic psychological stress exposure: Implications for cognitive decline in Zucker diabetic fatty rats

Figure 2. Effects of ZBPYR on plasma adrenocorticotropic hormone (ACTH) and corticosterone (CORT) during the stress intervention period in PSD rats. Plasma ACTH values were examined weekly. Plasma ACTH (A), ACTH AUC (B). Plasma corticosterone values were measured weekly. Plasma corticosterone (C), corticosterone AUC (D). **p <0.01, ***p <0.001, ****p <0.0001 PSD vs. ZDF; #p <0.05, ##p <0.01, ###p <0.001 PDZ vs. PSD (mean ± SEM, n=3 per group).