Research Paper Volume 12, Issue 22 pp 22744—22758

Geniposide ameliorated sepsis-induced acute kidney injury by activating PPARγ

Figure 2. Effect of GE on sepsis-induced kidney dysfunction. Levels of serum creatinine (Scr) (A), blood urea nitrogen (BUN) (B) and serum cystain C (ScysC) (C) in serum and α glutathione S transferase (α-GST) (F) and albumin (G) in urine were measured by an automatic biochemical analyzer. The levels of kidney injury molecule-1 (KIM1) (D) and IL-18 (E) were determined using their corresponding ELISA kits. The mRNA level and protein expression of NGAL were measured using qRT-PCR and western blot, respectively (H, I). ***p<0.001 vs="" the="" sham="" group.="" #,="" ##,="" ###p<0.05,="" 0.01,="" 0.001="" CLP="" group.<="" p="">