Research Paper Volume 13, Issue 2 pp 1872—1882

Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer

Characterization of MWNT/Sor/siRNA. (A) The representative images of MWNT/Sor/siRNA using scanning electron microscope. (B) The representative images of MWNT/Sor/siRNA using transmission electron microscopy. (C) The ultraviolet visible absorption spectra of MWNT/Sor/siRNA. (D) Gel retardation assay of naked siRNA and MWNT/Sor/siRNA complexes with the different N/P ratio. (E) Cumulative drug release profiling of MWNT/Sor and MWNT/Sor/siRNA in PBS (pH 7.4 and pH 5.0).

Figure 1. Characterization of MWNT/Sor/siRNA. (A) The representative images of MWNT/Sor/siRNA using scanning electron microscope. (B) The representative images of MWNT/Sor/siRNA using transmission electron microscopy. (C) The ultraviolet visible absorption spectra of MWNT/Sor/siRNA. (D) Gel retardation assay of naked siRNA and MWNT/Sor/siRNA complexes with the different N/P ratio. (E) Cumulative drug release profiling of MWNT/Sor and MWNT/Sor/siRNA in PBS (pH 7.4 and pH 5.0).