Research Paper Volume 12, Issue 20 pp 20493—20511

RNA-seq reveals the diverse effects of substrate stiffness on epidermal ovarian cancer cells

Figure 2. Spread area, circularity and aspect ratio of cell and nucleus correlate with substrate rigidity. Spread area (A and B), circularity (C and D) and aspect ratio (E and F) of SKOV-3 cells and nucleus were analyzed using ImageJ software. Each column represents means ± SE of 40-60 cells from 2 independent experiments. *P < 0.05, ***P <0.001, ****P < 0.0001.