Research Paper Volume 12, Issue 21 pp 21518—21543

Oncostatin M expression and TP53 mutation status regulate tumor-infiltration of immune cells and survival outcomes in cholangiocarcinoma

Figure 5. Identification of Immune Related Hub Gene OSM of CCA Patients with and without TP53 Mutations. (A) Volcano plot of TP53wild and TP53mutant group from TCGA dataset; (B) DEGs PPI network of TP53wild and TP53mutant group; (C) Top10 immune related genes were filtered from TP53 mutation associated DEGs by calculating the nodes scores of genes; (D) Overall survival of the Top10 immune related genes analyzed by KM curve analysis and log-rank test.