Research Paper Volume 12, Issue 22 pp 22794—22813

Integrative analysis of transcriptomes highlights potential functions of transfer-RNA-derived small RNAs in experimental intracerebral hemorrhage

Figure 6. Bioinformatics analysis revealing potential biological functions of 7 ICH-responsive tsRNAs. (A) Top 10 enriched biological functions ranked by the number of enriched genes and colored by P-value are shown using the Metascape online database. (B) tsRNA-mRNA-pathway interaction networks. tsRNAs could target mRNA and affect their expression level in a miRNA-like manner. Then, the altered mRNAs affect the corresponding pathways to alter biological functions.