Research Paper Volume 12, Issue 20 pp 20587—20610

Multiomics integrative analysis for gene signatures and prognostic values of m6A regulators in pancreatic adenocarcinoma: a retrospective study in The Cancer Genome Atlas project


Landscape of somatic mutation status of m6A regulators in PAAD. (A) The mutation frequency of 24 m6A regulators in 177 patients from TCGA_PAAD cohort. Each column represented individual patients. The upper barplot showed tumor mutation burden (TMB). (B) The mutation frequency of 24 m6A regulators in 616 patients from ICGC_AU_PAAD and ICGC_CA_PAAD cohort. The upper barplot showed mutation events happeded in per 1 million bases. Due to the difference in the definition and naming of somatic mutations, it is unable to integrate (A) and (B) into the same waterfall chart.