Research Paper Volume 12, Issue 21 pp 21597—21612

Construction and validation of an immunity-related prognostic signature for breast cancer

Figure 4. Regulatory network of survival-associated immunity-related genes based on differentially-expressed transcription factors. (A) Highlight of up- and down-regulated transcription factors in breast cancer. (B) The regulatory network between transcription factors and prognostic immunity-related genes. Survival-associated immunity-related genes are shown in ellipses and differentially-expressed transcription factors in diamonds. A pink line represents positive regulation and a blue line represents negative regulation.