Research Paper Volume 12, Issue 20 pp 20645—20657

Hsa_circ_0081534 increases the proliferation and invasion of nasopharyngeal carcinoma cells through regulating the miR-508-5p/FN1 axis


Silencing of hsa_circ_0081534 induced a reduction in the progression of NPC cells in vitro. (AC) Relative expression of hsa_circ_0081534 in NPC tissues and cell lines. (D, E) qRT-PCR assessment of interference efficiencies of si-circ_0081534 in NPC cells. (F, G) Cell proliferation after silencing hsa_circ_0081534 was assessed by MTT assay. (H, I) Transwell assay was used to determine NPC cells invasion ability in vitro. NT: adjacent normal tissues; NPC: nasopharyngeal carcinoma tissues. *P < 0.05.