Research Paper Volume 12, Issue 20 pp 20645—20657

Hsa_circ_0081534 increases the proliferation and invasion of nasopharyngeal carcinoma cells through regulating the miR-508-5p/FN1 axis


miR-508-5p mimics decreased NCP cells proliferation and invasion. (A, B) miR-508-5p expression in NPC tissues and cell lines. (C) MiR-508-5p expression was negatively correlated with hsa_circ_0081534 expression in NPC tissues. (D) Transfected efficiency of miR-508-5p mimics in HONE1 cells was determined by qRT-PCR. (E, F) miR-508-5p overexpression induced a subsequent reduction in HONE1 cells proliferation and invasion abilities. *P < 0.05.