Research Paper Volume 12, Issue 20 pp 20645—20657

Hsa_circ_0081534 increases the proliferation and invasion of nasopharyngeal carcinoma cells through regulating the miR-508-5p/FN1 axis


FN1 was a target of miR-508-5p. (A) Venn diagram indicating potential targets explored by MicroT-CDS and TCGA databases. (B) Predicted binding sites between miR-508-5p and FN1. (C) The secondary structure of miR-508-5p. (D) Examinations of combinations between miR-508-5p and FN1 were verified by dual-luciferase reporter assays in NPC cells. (E) FN1 expression was detected by qRT-PCR in NPC cells transfected with either miR-NC or miR-508-5p mimics. *P < 0.05.