Research Paper Volume 12, Issue 19 pp 19641—19659

Identification of immune landscape signatures associated with clinical and prognostic features of hepatocellular carcinoma

Figure 7. Evaluation of clinical outcomes based on differential TIICs. (A) Relative proportions of 22 immune cell subpopulations in HCC patients. (B) Heatmap visualization of differential immune cell proportions between Immunity_H and Immunity_L. (C) Violin plot analysis exhibiting distinct immune cells subpopulation between Immunity_H and Immunity_L. (D) Correlation matrix of all 22 immune cell proportions in HCC. (E) Box plot depicting relationships between TIICs and pathologic grade, as well as the clinical stage (Kruskal-Wallis tests). (F) Kaplan-Meier survival curves show the relationship between TIICs and survival. (G) The regulation networks among prognostic TIICs, IRG panel, and stromal cell content-related DEG panel. Green and blue represent protective factors. Red and orange represent the opposite.