Research Paper Volume 13, Issue 2 pp 1883—1897

CD36 upregulates DEK transcription and promotes cell migration and invasion via GSK-3β/β-catenin-mediated epithelial-to-mesenchymal transition in gastric cancer

CD36 knockdown inhibits EMT in GC cells. (A) Morphological changes in SNU-216 cells transfected with NC/siCD36 (phase contrast microscopy, 200×). (B) Western blot analysis of EMT markers in SNU-216 cells transfected with NC/siCD36. Data are presented as the mean ± SD. GAPDH was used as endogenous control. (C) Immunofluorescence staining for E-cadherin and vimentin in SNU-216 cells transfected with NC/siCD36. *p

Figure 3. CD36 knockdown inhibits EMT in GC cells. (A) Morphological changes in SNU-216 cells transfected with NC/siCD36 (phase contrast microscopy, 200×). (B) Western blot analysis of EMT markers in SNU-216 cells transfected with NC/siCD36. Data are presented as the mean ± SD. GAPDH was used as endogenous control. (C) Immunofluorescence staining for E-cadherin and vimentin in SNU-216 cells transfected with NC/siCD36. *p < 0.05 vs. NC group.