Research Paper Volume 12, Issue 19 pp 19660—19676
Anticancer effects of miR-124 delivered by BM-MSC derived exosomes on cell proliferation, epithelial mesenchymal transition, and chemotherapy sensitivity of pancreatic cancer cells
The miR-124-mimic transfection inhibited the invasion, migration of AsPC-1 and PANC1 cells, which were partly reversed by the miR-124 inhibitor or EZH2 overexpression. The capability of cell invasion was determined by transwell assay (A). The wound-healing assay was used for measurement for cell migration (B).