Research Paper Volume 12, Issue 19 pp 19660—19676

Anticancer effects of miR-124 delivered by BM-MSC derived exosomes on cell proliferation, epithelial mesenchymal transition, and chemotherapy sensitivity of pancreatic cancer cells


EZH2 is a target of miR-124. The binding site between miR-124 and EZH2 was predicted (A), dual-luciferase reporter systems were built (B) and the report data illustrated that EZH2 is the target gene of miR-124-3p. The expression of EZH2 in miR-124 inhibitor-treated cells were determined by western blot (C, D). These results were presented as the mean ± standard deviation (SD) of three independent experiments. **P<0.01.