Figure 10. The correlation between the genes in the modules and grade. (A) Distribution of mean gene significance and standard deviation with grade in the HNSCC modules. (B) Scatter plot of the module eigengenes in the turquoise, black, and red modules. (C) The lncRNA-mRNA network (weight>0.1) of the hub lncRNAs in the turquoise module. Red and blue diamond shapes represent up- and downregulated lncRNAs, respectively. Purple circles represent mRNAs. GO (D–F) and KEGG (G) pathway enrichment of eight modules. GO enrichment contains three categories: biological process (D), cellular component (E) and molecular function (F).