Research Paper Volume 12, Issue 20 pp 20778—20800

Identification of a nomogram based on an 8-lncRNA signature as a novel diagnostic biomarker for head and neck squamous cell carcinoma


WGCNA. (A) Analysis of the scale-free topology model fit index for various soft-thresholding powers (β) and the mean connectivity for various soft-thresholding powers. Overall, 3 was the most fitting power value. (B) Dendrogram of the genes and different clinical factors of HNSCC (survival time, survival status, sex, age, grade, stage, T stage, N stage, M stage, new event, signature score). (C) Dendrogram of the gene modules based on a dissimilarity measure. The branches of the cluster dendrogram correspond to the different gene modules. Each piece of the leaves on the cluster dendrogram corresponds to a gene. (D). Module-trait relationships. Heatmap of the correlation between module eigengenes and clinical characteristics of HNSCC. (E) Hierarchical clustering and heatmap of the hub gene network.