Research Paper Volume 12, Issue 21 pp 21971—21991

CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1

Figure 6. In vitro functional analysis of STAP1 in NP cells. (A) The FISH results of the rescue experiment using the si STAP1, STAP1 and the control. The results suggested that STAP1 downregulated the expression of ADAMTS 5 and MMP13 and upregulated the expression of Collagen II and Aggrecan. (B) Western blot analysis (n=3) confirmed the results in (A). Data are the mean ± SEM.