Research Paper Volume 12, Issue 19 pp 19740—19755
Development of a five-protein signature for predicting the prognosis of head and neck squamous cell carcinoma
The prognostic value of HER3_pY1289 in HNSCC. (A) The staining intensity of HER3_pY1289 is higher in the high IHC score group compared to the low IHC score group (upper panels: scale bar=100 μm, lower panels: scale bar=100 μm). (B) A higher percentage of patients at the advanced stage is observed in the high IHC score group than in the low IHC score group. (C) A higher percentage of patients with positive lymph node metastasis is found in the high IHC score group. (D) A higher percentage of patients with positive HPV infection is found in the high IHC score group. (E) The survival analysis shows that the patients in the high IHC score group have worse OS than those in the low IHC score group.