Research Paper Advance Articles pp 23836—23848

Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression

Figure 1. High expression of hsa_circ_0001869 predicted unfavorable prognosis of non-small cell lung cancer (NSCLC). (A) qRT-PCR assay of hsa_circ_0001869 in 50 paired NSCLC tumor tissues and adjacent nontumor tissues. Data are expressed as mean ± SD. ***P < 0.001 vs. normal controls. (B) Fluorescent in situ hybridization indicates subcellular localization of hsa_circ_0001869. (C) Prognostic significance of hsa_circ_0001869 expression for hsa_circ_0001869 patients was performed with FISH using the median value as the cutoff. Observation time was 60 months. (D) Genomic loci of ZCCHC6 and hsa_circ_0001869. Red, back splicing.