Research Paper Advance Articles pp 23836—23848

Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression

Figure 7. hsa_circ_0001869 facilitated NSCLC progression in vivo by targeting miR-638 and upregulating FOSL2 expression. (A) Xenograft tumors in nude mice from four treatment groups (sh-NC, sh-circRNA, sh-circRNA + miR-638 inhibitor, and sh-circRNA + LV-FOSL2) after subcutaneous injection of A549 cells. (B) Xenograft volumes from four treatment groups measured at the indicated time points. n = 5. Data are expressed as mean ± SD. ***P < 0.001 vs. (C) Xenograft weights were compared among the groups. Data are expressed as mean ± SD. ***P < 0.001 vs. sh-NC.