Research Paper Advance Articles pp 23872—23888

Apigenin-7-O-β-D-(-6”-p-coumaroyl)-glucopyranoside treatment elicits a neuroprotective effect through GSK-3β phosphorylation-mediated Nrf2 activation

Figure 6. Effect of APG treatment on p-GSK-3β (Ser-9) expression and Nrf2 nuclear translocation. (A). APG treatment increased the phosphorylation of GSK-3β as compared with the I/R group. (B) The comprehensive photograph and analysis result of western-blot statistical analysis of Nrf2 in the control, I/R, and APG (50 mg/Kg) treatment groups. APG treatment increased Nrf2 nuclear expression as compared with the I/R group. n = 5 per group. * P < 0.05.