Figure 6. Correlation analysis between the expression of prognostic risk-related genes and clinicopathological features in high-risk and low-risk KIRP patients. (A) The heatmap shows the expression of the three prognostic signature-related genes in the low- and high-risk group KIRP patients stratified according to the clinicopathological parameters, namely, survival status (alive or dead), age (>65 y or <65 y), gender (male or female), AJCC stages (stages I, II, III or IV), T stage (T1-T4), N stage (N0, N1 or N2), and M stage (M0 or M1). Chi-square test evaluated the correlation between the clinicopathological parameters and prognostic risk. *P < 0.05, **P < 0.01 and ***P < 0.001. (B–E) The distribution of risk scores in high- and low-risk patients stratified according to (B) AJCC stage (stages I-II vs. stages III-IV), (D) T stage (T1-2 vs. T3-4), (D) N stage (N0 vs. N1-2) and (E) M stage (M0 vs. M1).