Research Paper Volume 12, Issue 21 pp 22078—22094

Prognostic risk signature based on the expression of three m6A RNA methylation regulatory genes in kidney renal papillary cell carcinoma


Figure 6. Correlation analysis between the expression of prognostic risk-related genes and clinicopathological features in high-risk and low-risk KIRP patients. (A) The heatmap shows the expression of the three prognostic signature-related genes in the low- and high-risk group KIRP patients stratified according to the clinicopathological parameters, namely, survival status (alive or dead), age (>65 y or <65 y), gender (male or female), AJCC stages (stages I, II, III or IV), T stage (T1-T4), N stage (N0, N1 or N2), and M stage (M0 or M1). Chi-square test evaluated the correlation between the clinicopathological parameters and prognostic risk. *P < 0.05, **P < 0.01 and ***P < 0.001. (BE) The distribution of risk scores in high- and low-risk patients stratified according to (B) AJCC stage (stages I-II vs. stages III-IV), (D) T stage (T1-2 vs. T3-4), (D) N stage (N0 vs. N1-2) and (E) M stage (M0 vs. M1).