Figure 5. ROC curve analysis for predicting the 6 non-coding RNAs as CRC diagnosis biomarkers. (A) ROC curve for the 6 non-coding RNAs signature to separate 60 CRC cases from 60 controls in the training set with the AUC presented in the right. (B) ROC curve analysis was used for the 6 non-coding RNAs signature to differentiate 597 CRC cases from 585 controls in the validation set with the AUC presented in the right. Factor1, 2, 3, 4, 5, 6 and merged represented the XLOC_001120, ENSG00000243766.2, miR-20b-5p, miR-329-3p, miR-374b-5p, miR-503-5p and the combination of the 6 non-coding RNAs.