Research Paper Advance Articles pp 23931—23944

Clinical and prognostic pan-cancer analysis of m6A RNA methylation regulators in four types of endocrine system tumors

Figure 2. Identification of consensus clusters by m6A RNA methylation regulators in endocrine system tumors. (AC) Consensus clustering matrix for k = 2, and consensus clustering cumulative distribution function (CDF) for k = 2 to 9, and relative change in area under CDF curve for k = 2–9, and principal component analysis (PCA) of total RNA expression profiles in tumors data from the cancer genome atlas (TCGA) dataset; (D, E) Heatmaps, and Kaplan–Meier overall survival (OS) curve and clinicopathologic features of two clusters defined by consistent expression of the m6A regulatory genes (clusters1/2).