Research Paper Volume 12, Issue 21 pp 22152—22173

Identification of novel prognosis-related genes in the endometrial cancer immune microenvironment

Figure 6. CD74, HLA-DRB5, CD52, HLA-DPB1, and HLA-DRB1 in the microenvironment of related prognostic markers in endometrial cancer. (A) Expression of CD74, HLA-DRB5, CD52, HLA-DPB1, HLA-DRB1, TNFRSF1B, and ACP5 in 41 endometrial cancer tissues and 20 normal tissues was determined by qRT-PCR. (B) ROC curve of 5 msicroenvironment-related prognostic signature. (C) Expression of CD74, HLA-DRB5, CD52, HLA-DPB1 and HLA-DRB1 was detected by immunohistochemistry in endometrial cancer (n = 42) and normal endometrial tissue (n = 20). Disease-free survival curves for CD74, HLA-DRB5, CD52, HLA-DPB1 and HLA-DRB1 in 42 endometrial carcinoma cases. *P < 0.05, **P < 0.01, ***P < 0.001.