Research Paper Volume 12, Issue 22 pp 23165—23186

An eleven metabolic gene signature-based prognostic model for clear cell renal cell carcinoma

Figure 3. Protein-protein interaction network and key co-expression modules. (A) The protein-protein interaction (PPI) network shows the interactions between 124 differentially expressed metabolic genes. (B, C) The two key modules consisting of co-expressing differentially expressed metabolic genes, module 1 and module 2 are shown. The red and green circles denote upregulated and downregulated metabolic genes, respectively.