Research Paper Volume 12, Issue 22 pp 23251—23274

Comprehensive circular RNA expression profiling constructs a ceRNA network and identifies hsa_circ_0000673 as a novel oncogene in distal cholangiocarcinoma

Figure 6. Validation of six differentially expressed circular (circ)RNAs by qRT-PCR. Three circRNAs, including hsa_circ_0000673 (A), hsa_circ_0008274 (B), and hsa_circ_0060144 (C) were significantly upregulated, and two circRNAs, including hsa_circ_0139402 (E) and hsa_circ_0001714 (F) were significantly downregulated in tumor tissues. (D) The level of hsa_circ_0072088 was not different between tumor and normal tissues. **p < 0.01, ***p < 0.001.