Research Paper Volume 12, Issue 22 pp 23251—23274

Comprehensive circular RNA expression profiling constructs a ceRNA network and identifies hsa_circ_0000673 as a novel oncogene in distal cholangiocarcinoma

Figure 7. A circular (circ)RNA-micro(mi)RNA-mRNA interacting network in dCCA. The network contains five dysregulated circRNAs, seven miRNAs, 260 mRNAs, and 17 hub genes. The node color changes from blue to red, representing the fold change of mRNA expression value in the cholangiocarcinoma cohort of The Cancer Genome Atlas (tumor versus normal).